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Daniel Tomé

Le Prof. Daniel Tomé est professeur de Nutrition humaine au “Paris Institute of Technology for Life, Food, and Environmental Sciences” (ParisAgroTech) où il préside également le département “Life Sciences and Health”. Il est également “visiting professor” à l’Université de Wageningen aux Pays-Bas. Le Prof. Tomé est une autorité mondiale dans le domaine de l’étude des protéines, de la fonction des acides aminés et de leurs implications pour les recommandations nutritionnelles et la qualité nutritionnelle. Daniel Tomé est l’auteur de plus de 230 “papers” et est membre de diverses commissions d’experts qui étudient les recommandations nutritionnelles.

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Protein quality affects bone status during moderate protein restriction in growing mice.

Adequate protein intake during development is critical to ensure optimal bone gain and to attain a higher...

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Current issues in determining dietary protein and amino-acid requirements.

Pregnancy and the first two years of life are periods of rapid growth and yet the knowledge of requirements...

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Digestibility issues of vegetable versus animal proteins: protein and amino acid requirements-functional aspects.

The article presents information on the functional aspects of the protein and amino acid requirement...

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Dietary fibers reduce food intake by satiation without conditioned taste aversion in mice.

It is well known that intake of dietary fiber (DF) potently decreases food intake and feelings of hunger...

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Isotopic and modeling investigation of long-term protein turnover in rat tissues.

Fractional synthesis rates (FSR) of tissue proteins (P) are usually measured using labeled amino acid...

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Beneficial effects of an amino acid mixture on colonic mucosal healing in rats.

BACKGROUND: Mucosal healing (MH) decreases the relapse risk in patients with inflammatory bowel disease,...

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Dietary proteins contribute little to glucose production, even under optimal gluconeogenic conditions in healthy humans.

Dietary proteins are believed to participate significantly in maintaining blood glucose levels, but their...

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Intestinal luminal nitrogen metabolism: role of the gut microbiota and consequences for the host

Alimentary and endogenous proteins are mixed in the small intestinal lumen with the microbiota. Although...

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Control of protein and energy intake - brain mechanisms

The protein content of the diet has long been investigated for its influence on food behaviour. High-protein...

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Energy restriction only slightly influences protein metabolism in obese rats, whatever the level of protein and its source in the diet.

High protein (HP) diets during energy restriction have been studied extensively regarding their ability...

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Sequential release of milk protein-derived bioactive peptides in the jejunum in healthy humans.

Background: The digestive hydrolysis of dietary proteins leads to the release of peptides in the intestinal...

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Comparative efficiency of microbial enzyme preparations versus pancreatin for in vitro alimentary protein digestion.

Utilisation of microbial enzymes may represent an alternative strategy to the use of conventional pancreatin...

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Identification of biomarkers for intake of protein from meat, dairy products and grains: a controlled dietary intervention study.

In the present controlled, randomised, multiple cross-over dietary intervention study, we aimed to identify...

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Criteria and markers for protein quality assessment - a review

Dietary proteins are found in animal products, plant products and single-cell organisms. Proteins are...

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Dietary protein affects gene expression and prevents lipid accumulation in the liver in mice.

BACKGROUND AND AIMS: High protein (HP) diets are suggested to positively modulate obesity and associated...

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Nutrient sensing and signalling by the gut

Recent advances highlight that nutrient receptors (such as T1R1/T1R3 heterodimer, Ca sensing receptor...

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Dietary fibers solubilized in water or an oil emulsion induce satiation through CCK-mediated vagal signaling in mice.

This study focused on the fate of the satiating potency of dietary fibers when solubilized in a fat-containing...

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Endogenous proteins in terminal ileal digesta of adult subjects fed a casein-based diet

Background: Although there are several published estimates of the endogenous amino acid composition of...

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Brain responses to high-protein diets.

Proteins are suspected to have a greater satiating effect than the other 2 macronutrients. After protein...

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Hydrolyzed collagen improves bone status and prevents bone loss in ovariectomized C3H/HeN mice.

This study evaluates the effect of hydrolyzed collagen (HC) on bone health of ovariectomized mice (OVX)...

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Protein status elicits compensatory changes in food intake and food preferences.

BACKGROUND: Protein is an indispensable component within the human diet. It is unclear, however, whether...

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Peripheral and central mechanisms involved in the control of food intake by dietary amino acids and proteins.

The present review summarises current knowledge and recent findings on the modulation of appetite by...

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A pilot study for the intrinsic labeling of egg proteins with 15N and 13C.

The aim of this study was to produce intrinsically and uniformly doubly (15)N-(13)C-labeled proteins....

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Quinoa extract enriched in 20-hydroxyecdysone protects mice from diet-induced obesity and modulates adipokines expression.

Besides their well-known effect in the molting control in insects, ecdysteroids are steroid hormones...

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Protein intake, calcium balance and health consequences

High-protein (HP) diets exert a hypercalciuric effect at constant levels of calcium intake, even though...

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Increasing protein at the expense of carbohydrate in the diet down-regulates glucose utilization as glucose sparing effect in rats.

High protein (HP) diet could serve as a good strategy against obesity, provoking the changes in energy...

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The nature of the dietary protein impacts the tissue-to-diet 15N discrimination factors in laboratory rats.

Due to the existence of isotope effects on some metabolic pathways of amino acid and protein metabolism,...

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Les protéines alimentaires: effets spécifiques sur la satiété et l'obésité

La qualité des protéines est reliée à sa composition en acides aminés essentiels. Les besoins en...

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Hydrolyzed collagen improves bone status and prevents bone loss in ovariectomized C3H/HeN mice.

This study evaluates the effect of hydrolyzed collagen (HC) on bone health of ovariectomized mice (OVX)...

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